Aug 11, 2020 · In the clinical staging of lymph node metastasis, defined criteria must be fulfilled for the diagnosis of clinical ENE. According to the new edition of the TNM classification, ENE in p16-positive OPSCC compared to HPV-negative tumors does not result in prognostic upstaging with regard to the N category or UICC stage. Dec 14, 2018 · Primary peritoneal serous carcinoma (PPSC) is a rare and aggressive tumor that originates from the peritoneal lining. This article provides a comprehensive review of the diagnosis, treatment, and prognosis of PPSC, based on six cases and relevant literature. To access the full text, click on the link below. Nov 17, 2019 · 3.3. p63 in the Prognosis of Merkel Cell Carcinoma. Merkel cell carcinoma (MCC) displays neuroendocrine features and is a rare but aggressive type of skin cancer. It mainly affects elderly patients (>75 years old) and can be caused by chronic UV exposure or Merkel cell polyomavirus. Mar 19, 2020 · The tumor-suppressor protein p16 is paradoxically overexpressed in cervical cancer (CC). Despite its potential as a biomarker, its clinical value and the reasons for its failure in tumor suppression remain unclear. Our purpose was to determine p16 clinical and biological significance in CC. p16 expression pattern was examined by immunohistochemistry in 78 CC cases (high-grade squamous .

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